Warning: require_once(d:\d58web\app/incs/inc.php) [function.require-once]: failed to open stream: Permission denied in E:\www\web\index.php on line 17

Fatal error: require_once() [function.require]: Failed opening required 'd:\d58web\app/incs/inc.php' (include_path='.;C:\php5\pear') in E:\www\web\index.php on line 17